Inge von Holtzendorff was born in Italy. Her father died of a lung diesease when she was only 9 months old. After her father’s death, her mother, Hermione, traveled the world and left her children behind with relatives and servants. Inge von Holtzendorff was eventually adopted by father’s sister, Margaret Holtzendorff in 1906. In 1911 both von Holtzendorff and her sister moved in with Hermione again in Berlin. Tragically, Hermione died suddenly from a stroke on December 12th, 1918.
In 1920, four of her plays were published. In 1923 she married the painter Conrad Westpfahl, whom she had met in 1920. Over the next few years Inge and her husband moved frequently. They lived in Dresden, Waltenhofen, Berlin, Paris, Italy, and Greece. Between 1934 and 1939 the family lived in many different cities in Greece, including Athens, Sparta, Mystras, Corinth, Mycenae, and Crete. Some of von Holtzendorff´s works were also translated into Greek while she still lived there.
In October 1974, von Holtzendorff died in a hospital in Würzburg. Her husband died shortly thereafter from loneliness and depression.